Frontier Magnetic Resonance Imaging

Prof. L.Ying

We are living in this most exciting era of human history, when science and technology are not only developing at an unprecedented rapid pace but also fundamentally changing the way we live, the way we work, and even the way we view ourselves. Biomedical imaging is one of the most important enabling technologies in this scientific revolution, which allows us to see objects, structures, and biological processes unreachable by human vision, providing tremendous opportunities to study biology, as well as diagnose and treat diseases.

The BRAIN group in the University of Wisconsin – Milwaukee (UWM) is dedicated to applying advances in physics, mathematics, and engineering to the development of advanced imaging capabilities to enable “real-time” observation of biological structures and processes for better understanding and treatment of diseases, and training future engineers and scientists the skills, values, and broad perspectives necessary for success in the global market place, for leadership in complex and multidisciplinary projects, and for a lifetime of continued learning.

Research Projects

  • Parallel magnetic resonance imaging using phased array coils (in collaboration with University of Illinois at Urbana-Champaign and GE Healthcare Technologies): funded by National Science Foundation, UW System Applied Research Grant, and Milwaukee Technical Assistance Grant
  • Dynamic contrast enhanced imaging of breast cancer (in collaboration with University of Pittsburgh Cancer Institute): funded by National Institute of Health
  • Chemical shift imaging for diagnosis of prostate cancer (in collaboration with Harvard Medical School)
  • Susceptibility artifacts reductions in functional magnetic resonance imaging (in collaboration with Medical College of Wisconsin): funded by Wisconsin Institute for Biomedical and Health Technologies
  • Phase unwrapping for magnetic resonance images
  • Generalized diffusion tensor imaging (in collaboration with ChangGung University, Taiwan)
  • Compressed Sensing

Facilities

The BRAIN laboratory has six PC workstations and a server (Dual Core Opteron 2GHz processors and 8GB RAM). The laboratory has access to the magnetic resonance imaging (MRI) facility at Medical College of Wisconsin located in Milwaukee, within easy commuting range of UWM. The facility has two GE Signa 3 Tesla whole-body MRI scanners with programmable pulse sequence capability and a Bruker 9.4 Tesla animal MRI scanner, both equipped with advanced parallel imaging capability. The laboratory also has access to the MRI scanners located at local GE Healthcare with granted modifications of hardware and software in actual MR systems.