Elizabeth Liedhegner, Ph.D.

Laboratory Manager II

[Image] Elizabeth Liedhegner

Enderis Hall, Room B41
Phone: (414) 229-5028
Fax: (414) 229-2619
liedhegn@uwm.edu

Department

Biomedical Sciences

Education

  • Post-Doctoral Fellow, Neuroscience Research Center,
    Medical College of Wisconsin, 2010
  • Ph.D., Pharmacology, Case Western Reserve University (Cleveland, OH), 2011
  • B.S., Biochemistry, Spring Hill College (Mobile, AL), 2004


Speaker Topics

  • Laboratory techniques

Interests & Expertise

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I am the laboratory manager of the research laboratories in the Biomedical Sciences Department. I am responsible for teaching graduate level classes and assisting graduate students and faculty in their research. I also facilitate the development and administration of outreach programs to promote biomedical careers.

My goal is to provide graduate students and faculty assistance in development of research projects, optimization of research protocols, and assistance with laboratory techniques. I hope to be a sounding board for graduate students to aid in their successful completion of the program. My expertise comes from 10 years of research experience where I was able to develop research goals and test hypotheses. I have successfully developed projects utilizing and troubleshooting multiple experimental techniques. My passion lies in the discovery of novel ideas and imparting my love of research to new students.


Recent Publications

Sabens Liedhegner, E., Sasman, A., & Hillard, C. J. (Under review). Brain Region-Specific Changes in N-Acylethanolamine Contents with Time of Day. Journal of Neurochemistry.

Sabens Liedhegner, E. A., Gao, X-H., & Mieyal, J. J. (2012). Mechanisms of Altered Redox Regulation in Neurodegenerative Diseases – Focus on Glutathionylation. Antioxidants and Redox Signaling, 16(6), 543-566.

Sabens Liedhegner, E. A., Stellar, K. M., & Mieyal, J. J. (2011). Levodopa activates ASK1 through Oxidative Dissociation of Protein Modulators and induces cell death. Journal of Chemical Research and Toxicology, 24, 1644-52.

Sabens, E. A., Distler, A. M., & Mieyal, J. J. (2010). Levodopa Deactivates Enzymes that Regulate Thiol-Disulfide Homeostasis and Promotes Neuronal Cell Death - Implications for Therapy of Parkinson’s Disease, Biochemistry, 30, 2715-2724.

Sabens, E. A., & Mieyal J. J. (2009). Glutaredoxin and Thioredoxin Enzyme Systems: Catalytic Mechanisms and Physiological Functions. In R. Massala & G. Mazza (Eds.), Glutathione and Sulfer Amino Acids in Human Health and Disease (pp. 121-156). Hoboken, New Jersey: John Wiley and Sons, Inc.

Mieyal, J. J., Gallogly, M. M., Qanungo, S., Sabens, E. A., & Shelton, M. D. (2008). Molecular Mechanisms and Clinical Implications of Reversible Protein S-Glutathionylation. Antioxid Redox Signal, 10, 1941-1988.

Offer, T., Ames, B. N., Bailey, S. W., Sabens, E. A., Nozawa, M., & Ayling, J. E. (2007). 5-Methyltetrahydrofolate Inhibits Photosensitization Reactions and Strand Breaks in DNA, FASEB J., 21, 2101-2107.


Honors & Awards

  • 2012: International Cannabinoid Research Symposium travel award (NIH)
  • 2011: International Cannabinoid Research Symposium travel award (NIH)
  • 2011: Postdoctoral poster presentation winner, Milwaukee Chapter Society of Neuroscience
  • 2010: 3rd place poster presentation, Research ShowCASE
  • 2010: Gordon Research Conference travel award (NSF)
  • 2009: Biomedical Graduate Student Symposium poster presentation winner
  • 2006: Greenfield Travel Award: Best journal club presentation CWRU Department of Pharmacology