University of Wisconsin–Milwaukee

School of Freshwater Sciences

CarvanMichael J. Carvan III

Shaw Associate Scientist, School of Freshwater Sciences

Phone: 414-382-1706
Fax: 414-382-1705


PhD, Veterinary Anatomy and Public Health, Texas A&M University, 1993
MS, Biological Oceanography, University of Miami, 1988
BS, Marine Biology, University of North Carolina at Wilmington, 1985

Research interests

  • Toxicology—the effects of toxic environmental chemicals on development, physiology, reproduction
  • Toxicogenomics—the effects of environmental chemical and other stressors on global gene expression
  • Epigenetics—the effects of developmental exposure to environmental chemicals and other stressors on adult disease or dysfunction—These effects are often heritable without a change in gene sequences
  • Behavioral toxicology—the effects of exposure to low-levels of environmental chemicals and other stressors and how they affect subtle non-lethal endpoints that are critical to survival
  • Gene-environment-disease/dysfunction interactions—species and individuals vary in their sensitivity to environmental stressors and in the vast majority of cases this difference can only be explained by complex interactions between genes and the environment

Recent and selected publications

Watanabe K, Andersen M, Basu N, Carvan III M, Crofton K, King K, Suñol C, Tiffany-Castiglioni E, and Schultz I. Defining and modeling known adverse outcome pathways: Domoic acid and neuronal signaling as a case study. Accepted Environmental Toxicology and Chemistry manuscript online: 20 OCT 2010 06:14PM EST | DOI: 10.1002/etc.373.

Smith LE, Carvan III MJ, White DC, Williams FE, and Weber DN. 2010. Selenomethionine attenuates early life stage abnormalities but not adult learning deficits in zebrafish developmentally exposed to methylmercury. Neurotoxicology and Teratology 32: 246-55.

Kusik BW, Carvan III MJ, Udvadia AJ. 2008. Detection of mercury in aquatic environments using EPRE reporter zebrafish. Marine Biotechnology 10: 750-757.

Carvan III MJ, Incardona JP, and Rise ML. 2008. Meeting the challenges of aquatic vertebrate ecotoxicology. BioScience 58: 1015-1025.

Carvan III MJ, Heiden TK, and Tomasiewicz HT. 2005. The utility of zebrafish as a model for toxicological research, pp 3-41. In T.W. Moon and T.P. Mommsen, eds., Biochemistry and Molecular Biology of Fishes, Volume 6: Environmental Toxicology, Elsevier, Amsterdam.