Mass Spectrometry Lab/ICP

The department of Chemistry and Biochemistry currently houses three mass spectrometers that support research programs ranging from routine analysis of organic compounds to detection of trace metals in environmental samples.

The VG Autospec, manufactured by Fisons (now Waters/Micromass), is the most versatile of the available Mass Spectrometry instruments at the Department of Chemistry and Biochemistry. It is a double focusing, triple sector mass spectrometer with a photomultiplier detection system. A range of ionization techniques are available with the Autospec, including electron impact (EI), chemical ionization (CI), liquid secondary ion mass spectrometry (LSIMS), fast atom bombardment (FAB), and electrospray ionization (ESI). The Autospec is a high-resolution mass spectrometer with a resolution of up to 20,000. The Autospec is used for analysis of molecules less than 2,000 Daltons, and can detect samples of most organic compounds at sub-nanogram quantities.

The Platform inductively coupled plasma mass spectrometer (ICP-MS), manufactured by GV Instruments Ltd., is an advanced, high-performance elemental analysis system that provides outstanding analytical performance. Detection limits for most elements are in the ppt range, including elements such as K, Ca, Fe, Se and As. The Mass range is 4-300 amu and the Resolution capability is 0.5 amu at 10% peak height.

Finally, the gas chromatograph mass spectrometer system consists of an HP 5890 GC interfaced to a HP 5971 Mass Selective Detector Quadrupole Mass Spectrometer. This system uses electron impact (EI) ionization to produce mass spectra and is capable of performing full mass scans or selective ion monitoring (SIM) of one or more specific masses. The system is used for the analysis of volatile to semivolatile organic compounds.

Mass Spectrometry Lab
Contact: Zhiqiang (Mark) Wang
E-mail: wang56@uwm.edu
Location: CHM B1 and B86
Phone: 414-229-4919